TANAKA Kazuki
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Assistant Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Outcomes of Renal Transplant Recipients after Percutaneous Coronary Intervention.
Journal Formal name：The American journal of cardiology
Abbreviation：Am J Cardiol
ISSN code：0002-9149/1879-1913
Domestic / ForeginForegin
Publisher Elsevier B.V.
Volume, Issue, Page pp.in press
Author and coauthor NAKAO Masashi†, YAMAGUCHI Junichi*, SATOMI Natsuko, EBIHARA Suguru, TANAKA Kazuki, OOTSUKI Hisao, INAGAKI Yusuke, JUJO Kentaro, ARASHI Hiroyuki, HAGIWARA Nobuhisa
Publication date 2020/02
Summary Renal transplantation (RT) can improve life expectancy in hemodialysis (HD) patients. However, little is known about the outcomes of renal transplant recipients after percutaneous coronary intervention (PCI). This study aimed to elucidate the effect of RT on clinical outcomes after PCI. Renal transplant recipients who underwent PCI from 2002 to 2017 were enrolled. To evaluate the effectiveness of RT, we retrospectively reviewed HD patients who underwent PCI. Propensity-score matching was performed using logistic regression to control for differences in baseline characteristics. The primary outcome was the incidence of major adverse cardiac events. After propensity matching, patients were classified into the RT (n = 50) group and HD (n = 50) group. Kaplan-Meier analysis revealed that the incidence of major adverse cardiac events was significantly lower in the RT group than in the HD group (p < 0.0001). Moreover, RT was associated with a lower risk for all-cause death (odds ratio 0.04; 95% confidence interval 0.002 to 0.03; p = 0.0054) and target vessel revascularization (OR 0.27; 95% CI 0.07 to 0.79; p = 0.015). RT may improve clinical outcomes after PCI, and it is encouraged for HD patients to increase life expectancy and reduce the occurrence of adverse events after PCI. Further research would be warranted to support this finding.
DOI 10.1016/j.amjcard.2020.02.007
PMID 32139159