Koichiro Yano
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Associate Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Effects of Locomotion Training on the Physical Functions and Quality of Life in Patients with Rheumatoid Arthritis: A Pilot Clinical Trial.
Journal Formal name:Progress in rehabilitation medicine
Abbreviation:Prog Rehabil Med
ISSN code:24321354/24321354
Domestic / ForeginForegin
Volume, Issue, Page 7,pp.20220014
Author and coauthor Mochizuki Takeshi, Kurata Aiko, Yano Koichiro, Ikari Katsunori, Okazaki Ken
Publication date 2022
Summary Objectives:This study investigated the effects of locomotion training on physical functions and quality of life in patients with rheumatoid arthritis (RA).Methods:Thirty-five patients with RA underwent locomotion training for 6 months. Health data collected from the subjects at baseline and after 6 months were the Health Assessment Questionnaire Disability Index (HAQ-DI), pain Visual Analog Scale, 10-m walking test, Timed Up-and-Go (TUG) test, single-leg standing test, Short Form-8 score with physical and mental component summaries, and 25-question Geriatric Locomotive Function Scale. The primary endpoint was a change in HAQ-DI at 6 months.Results:In terms of the primary outcome, the HAQ-DI significantly improved from 0.48 ± 0.69 at baseline to 0.27 ± 0.36 at 6 months (P=0.011). The significant secondary outcomes were a change in TUG test for comfortable walking from 9.8 ± 2.1 s at baseline to 8.9 ± 2.0 s at 6 months (P=0.002) and increased single-leg standing times for the right and left legs from 24.7 ± 23.5 s and 22.6 ± 22.8 s at baseline to 30.9 ± 22.1 s and 32.4 ± 24.1 s at 6 months (P=0.004, P <0.001), respectively.Conclusions:The findings suggest that locomotion training for 6 months may improve the HAQ-DI in patients with RA.
DOI 10.2490/prm.20220014
PMID 35434407