KISHI Takayuki
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Assistant Professor
Article types Original article
Language English
Peer review Non peer reviewed
Title Childhood-Onset Anti-Ku Antibody-Positive Generalized Morphea with Polymyositis: A Japanese Case Study.
Journal Formal name:Pediatric dermatology
Abbreviation:Pediatr Dermatol
ISSN code:(1525-1470)0736-8046(Linking)
Domestic / ForeginForegin
Volume, Issue, Page 32(5),pp.e224-5
Author and coauthor Kishi Takayuki, Miyamae Takako, Morimoto Ryoko, Ishiguro Naoko, Hamaguchi Yasuhito, Fujimoto Manabu, Nagata Satoru, Yamanaka Hisashi
Authorship Lead author
Publication date 2015/09
Summary We report a 16-year-old Japanese girl with anti-Ku antibody-positive generalized morphea and polymyositis who, at the age of 7 years, developed multiple brownish plaques on her left forearm that gradually extended to her upper arm, back, and left thigh, which a skin biopsy revealed as morphea. Laboratory testing was positive for antinuclear antibody and a high serum creatine kinase level. Although there were no clinical signs of muscular involvement, magnetic resonance imaging revealed findings consistent with myositis. The patient is one of the youngest reported cases positive for anti-Ku antibody. Anti-Ku positivity concomitant with generalized morphea is rare.
DOI 10.1111/pde.12644
PMID 26205636