ミウラ　イサム   ISAMU Miura   三浦　勇    所属   医学部 医学科（東京女子医科大学病院）    職種   助教
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Lumbar Ganglioneuroma from the Paravertebral Body Presenting in Continuity Between Intradural and Extradural Spaces.
掲載誌名	正式名：World neurosurgery 略　 称：World Neurosurg ISSNコード：18788769/18788750
掲載区分	国外
巻・号・頁	128,pp.289-294
著者・共著者	Takebayashi Kento, Kohara Kotaro, Miura Isamu, Yuzurihara Masahito, Kubota Motoo, Kawamata Takakazu
発行年月	2019/08
概要	BACKGROUND:Ganglioneuroma is a well-differentiated benign tumor that develops from the ganglion cells of the posterior mediastinum, retroperitoneum, cervical spine, and adrenal glands. The paravertebral body, in which the sympathetic trunk exists, is a common tumor site, and tumor sometimes invades the spinal canal through the intervertebral foramen. There have been no reports regarding tumors with intradural and extradural continuity. We report a paravertebral ganglioneuroma extending between the intradural and extradural spaces and its surgical treatment.CASE DESCRIPTION:A 33-year-old man was admitted to the hospital with progressive left lower limb numbness. A dumbbell-type tumor progressing to the spinal canal via the left intervertebral foramen from the paravertebral body at L1-2 was detected, and intradural calcified lesions were found. Pathologic examination of a computed tomography-guided biopsy sample revealed a ganglioglioma. The extradural tumor was removed; however, the left lower limb pain gradually worsened. As complete block was observed on myelography, the intradural tumor was removed 8 months later. Intraoperative findings revealed that the intradural and extradural tumors were continuous through the L1 nerve root.CONCLUSIONS:This is the first known reported case of paravertebral ganglioneuroma presenting in continuity between the intradural and extradural spaces.
DOI	10.1016/j.wneu.2019.05.065
PMID	31102769