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MARUKO Ruka
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Endowed Assistant Professor |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Half-dose photodynamic therapy for chronic central serous chorioretinopathy evaluated by focal macular electroretinograms. |
| Journal | Formal name：Japanese journal of ophthalmology Abbreviation：Jpn J Ophthalmol ISSN code：16132246/00215155 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 61(3),pp.260-266 |
| Author and coauthor | Oiwa Kazuhiro, Kataoka Keiko, Maruko Ruka, Ueno Shinji, Ito Yasuki, Terasaki Hiroko |
| Publication date | 2017/05 |
| Summary | PURPOSE:To evaluate the effect of half-dose verteporfin photodynamic therapy (hPDT) on the physiology of the macula determined by focal macular electroretinograms (FMERGs) in eyes with chronic central serous chorioretinopathy (CSC).METHODS:Fourteen eyes of 13 patients with chronic CSC were treated with hPDT. The best-corrected visual acuity (BCVA) was measured, and optical coherence tomography (OCT) and FMERGs were performed at the baseline, and at 4 days, 1, 3, 6, and 12 months after the hPDT.RESULTS:The subreitnal fluid was resolved in 12 of the 14 eyes after the hPDT. The amplitude of the a-wave at 12 months was significantly increased by 1.28 times over that at the baseline. The amplitude of the b-wave was also increased but not significantly (P = 0.055). The implicit time of the a-wave was significantly reduced at 6 months, and that of the b-wave at 3 months. The amplitudes of the oscillatory potentials did not change significantly during the 12-month follow-up period.CONCLUSIONS:hPDT led to an improvement in the FMERGs for at least 12 months without a transient depression of the FMERGs in eyes with chronic CSC. hPDT can be used safely to treat eyes with CSC. |
| DOI | 10.1007/s10384-017-0498-9 |
| PMID | 28154953 |