マルコ　ルカ   MARUKO Ruka   丸子　留佳    所属   医学部 医学科（東京女子医科大学病院）    職種   寄附部門助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Half-dose photodynamic therapy for chronic central serous chorioretinopathy evaluated by focal macular electroretinograms.
掲載誌名	正式名：Japanese journal of ophthalmology 略　 称：Jpn J Ophthalmol ISSNコード：16132246/00215155
掲載区分	国外
巻・号・頁	61(3),pp.260-266
著者・共著者	Oiwa Kazuhiro, Kataoka Keiko, Maruko Ruka, Ueno Shinji, Ito Yasuki, Terasaki Hiroko
発行年月	2017/05
概要	PURPOSE:To evaluate the effect of half-dose verteporfin photodynamic therapy (hPDT) on the physiology of the macula determined by focal macular electroretinograms (FMERGs) in eyes with chronic central serous chorioretinopathy (CSC).METHODS:Fourteen eyes of 13 patients with chronic CSC were treated with hPDT. The best-corrected visual acuity (BCVA) was measured, and optical coherence tomography (OCT) and FMERGs were performed at the baseline, and at 4 days, 1, 3, 6, and 12 months after the hPDT.RESULTS:The subreitnal fluid was resolved in 12 of the 14 eyes after the hPDT. The amplitude of the a-wave at 12 months was significantly increased by 1.28 times over that at the baseline. The amplitude of the b-wave was also increased but not significantly (P = 0.055). The implicit time of the a-wave was significantly reduced at 6 months, and that of the b-wave at 3 months. The amplitudes of the oscillatory potentials did not change significantly during the 12-month follow-up period.CONCLUSIONS:hPDT led to an improvement in the FMERGs for at least 12 months without a transient depression of the FMERGs in eyes with chronic CSC. hPDT can be used safely to treat eyes with CSC.
DOI	10.1007/s10384-017-0498-9
PMID	28154953