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マルコ ルカ
MARUKO Ruka
丸子 留佳 所属 医学部 医学科（東京女子医科大学病院） 職種 寄附部門助教 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | One-Year Outcomes of 1 + pro re nata versus 3 + pro re nata Intravitreal Aflibercept Injection for Neovascular Age-Related Macular Degeneration. |
| 掲載誌名 | 正式名：Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 略 称：Ophthalmologica ISSNコード：14230267/00303755 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 237(2),pp.105-110 |
| 著者・共著者 | Takayama Kei, Kaneko Hiroki, Sugita Tadasu, Maruko Ruka, Hattori Kyoko, Ra Eimei, Kawano Kenichi, Kataoka Keiko, Ito Yasuki, Terasaki Hiroko |
| 発行年月 | 2017 |
| 概要 | PURPOSE:We compared 1-year outcomes of 1 + pro re nata (PRN) versus 3 + PRN of intravitreal aflibercept injection (IAI) for age-related macular degeneration (AMD).METHODS:Forty-two eyes with naïve AMD received 3 + PRN IAI treatment and 47 eyes with naïve AMD received 1 + PRN IAI treatment. Visual acuity (VA), central retinal thickness (CRT), and central choroidal thickness (CCT) and number of administered IAIs during 12 months were compared.RESULTS:VAs improved, and CRTs reduced significantly at any given month from baseline in both groups (p < 0.01, respectively). CCT reduced significantly at 3 months in the 3 + PRN group (p = 0.024) but not in the 1 + PRN group. The 1 + PRN group received fewer injections than the 3 + PRN group (p < 0.01).CONCLUSIONS:Aflibercept leads to equivalent VA and morphologic retinal improvement without administering 3 injections. |
| DOI | 10.1159/000461785 |
| PMID | 28231566 |