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Ryoko Sakai
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Nationwide clinical and epidemiological study of large-vessel vasculitis in Japan in 2017. |
| Journal | Formal name：Modern rheumatology Abbreviation：Mod Rheumatol ISSN code：14397609/14397595 |
| Volume, Issue, Page | pp.- |
| Author and coauthor | Konda Naoko, Sakai Ryoko, Saeki Keigo, Matsubara Yuri, Nakamura Yosikazu, Miyamae Takako, Nakaoka Yoshikazu, Harigai Masayoshi |
| Publication date | 2023/02 |
| Summary | OBJECTIVE:We conducted a nationwide epidemiological study to estimate the number of patients with Takayasu arteritis (TAK) and giant cell arteritis (GCA) in Japan and to describe the clinical characteristics of these patients.METHODS:The first survey was designed to estimate the number of patients with TAK and GCA who were treated at medical institutions in Japan in 2017. The second survey was designed to collect data on the clinical characteristics of the patients who were reported in the first survey.RESULTS:Of the 3,495 institutions selected for the first survey, 1,960 (56.1%) responded. The number of patients with clinically diagnosed TAK and GCA was estimated to be 5,320 (95% confidence interval [CI], 4,810-5,820) and 3,200 (95% CI, 2,830-3,570), respectively. Aortic regurgitation was reported in 35% of patients with TAK, and eye-related comorbidities were observed in 30.4% of patients with GCA. The common carotid and internal carotid arteries were the most frequently involved in patients with TAK (62.7%). Subclavian artery lesions and thoracic or abdominal aorta lesions were reported in 31% and 42.6% of patients with GCA, respectively.CONCLUSIONS:The number of patients with TAK and GCA was estimated simultaneously, and significant differences in clinical characteristics were observed between the two diseases. |
| DOI | 10.1093/mr/road019 |
| PMID | 36737863 |