サカイ　リヨウコ   Ryoko Sakai   酒井　良子    所属   医学部 医学科（東京女子医科大学病院）    職種   非常勤講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Nationwide clinical and epidemiological study of large-vessel vasculitis in Japan in 2017.
掲載誌名	正式名：Modern rheumatology 略　 称：Mod Rheumatol ISSNコード：14397609/14397595
巻・号・頁	pp.-
著者・共著者	Konda Naoko, Sakai Ryoko, Saeki Keigo, Matsubara Yuri, Nakamura Yosikazu, Miyamae Takako, Nakaoka Yoshikazu, Harigai Masayoshi
発行年月	2023/02
概要	OBJECTIVE:We conducted a nationwide epidemiological study to estimate the number of patients with Takayasu arteritis (TAK) and giant cell arteritis (GCA) in Japan and to describe the clinical characteristics of these patients.METHODS:The first survey was designed to estimate the number of patients with TAK and GCA who were treated at medical institutions in Japan in 2017. The second survey was designed to collect data on the clinical characteristics of the patients who were reported in the first survey.RESULTS:Of the 3,495 institutions selected for the first survey, 1,960 (56.1%) responded. The number of patients with clinically diagnosed TAK and GCA was estimated to be 5,320 (95% confidence interval [CI], 4,810-5,820) and 3,200 (95% CI, 2,830-3,570), respectively. Aortic regurgitation was reported in 35% of patients with TAK, and eye-related comorbidities were observed in 30.4% of patients with GCA. The common carotid and internal carotid arteries were the most frequently involved in patients with TAK (62.7%). Subclavian artery lesions and thoracic or abdominal aorta lesions were reported in 31% and 42.6% of patients with GCA, respectively.CONCLUSIONS:The number of patients with TAK and GCA was estimated simultaneously, and significant differences in clinical characteristics were observed between the two diseases.
DOI	10.1093/mr/road019
PMID	36737863