小島 光暁
   Department   Other, Other
   Position  
Article types Original article
Language English
Peer review Peer reviewed
Title Vagus nerve stimulation modulates arachidonic acid production in the mesenteric lymph following intestinal ischemia-reperfusion injury.
Journal Formal name:The journal of trauma and acute care surgery
Abbreviation:J Trauma Acute Care Surg
ISSN code:21630763/21630755
Domestic / ForeginForegin
Volume, Issue, Page 91(4),pp.700-707
Author and coauthor Nakatsutsumi Keita, Morishita Koji, Yagi Masayuki, Doki Sanae, Watanabe Arisa, Ikegami Nahoko, Kobayashi Testuyuki, Kojima Mitsuaki, Senda Atsushi, Yamamoto Kouhei, Aiboshi Junichi, Coimbra Raul, Otomo Yasuhiro
Publication date 2021/10
Summary BACKGROUND:Inflammatory lipid mediators in mesenteric lymph (ML), including arachidonic acid (AA), are considered to play an important role in the pathogenesis of multiple-organ dysfunction after hemorrhagic shock. A previous study suggested that vagus nerve stimulation (VNS) could relieve shock-induced gut injury and abrogate ML toxicity, resulting in the prevention of multiple-organ dysfunction. However, the detailed mechanism of VNS in lymph toxicity remains unclear. The study aimed to investigate the relationship between VNS and inflammatory lipid mediators in
DOI 10.1097/TA.0000000000003345
PMID 34238858