コジマ ミツアキ
  小島 光暁
   所属   その他 その他
   職種   嘱託医師
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Vagus nerve stimulation modulates arachidonic acid production in the mesenteric lymph following intestinal ischemia-reperfusion injury.
掲載誌名 正式名:The journal of trauma and acute care surgery
略  称:J Trauma Acute Care Surg
ISSNコード:21630763/21630755
掲載区分国外
巻・号・頁 91(4),pp.700-707
著者・共著者 Nakatsutsumi Keita, Morishita Koji, Yagi Masayuki, Doki Sanae, Watanabe Arisa, Ikegami Nahoko, Kobayashi Testuyuki, Kojima Mitsuaki, Senda Atsushi, Yamamoto Kouhei, Aiboshi Junichi, Coimbra Raul, Otomo Yasuhiro
発行年月 2021/10
概要 BACKGROUND:Inflammatory lipid mediators in mesenteric lymph (ML), including arachidonic acid (AA), are considered to play an important role in the pathogenesis of multiple-organ dysfunction after hemorrhagic shock. A previous study suggested that vagus nerve stimulation (VNS) could relieve shock-induced gut injury and abrogate ML toxicity, resulting in the prevention of multiple-organ dysfunction. However, the detailed mechanism of VNS in lymph toxicity remains unclear. The study aimed to investigate the relationship between VNS and inflammatory lipid mediators in
DOI 10.1097/TA.0000000000003345
PMID 34238858