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小島 光暁
Department Other, Other Position |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Enteric glia cells are critical to limiting the intestinal inflammatory response after injury. |
| Journal | Formal name：American journal of physiology. Gastrointestinal and liver physiology Abbreviation：Am J Physiol Gastrointest Liver Physiol ISSN code：15221547/01931857 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 312(3),pp.G274-G282 |
| Author and coauthor | Langness Simone, Kojima Mitsuaki, Coimbra Raul, Eliceiri Brian P, Costantini Todd W |
| Authorship | 2nd author |
| Publication date | 2017/03 |
| Summary | Vagal nerve stimulation (VNS) has been shown to limit intestinal inflammation following injury; however, a direct connection between vagal terminals and resident intestinal immune cells has yet to be identified. We have previously shown that enteric glia cell (EGC) expression is increased after injury through a vagal-mediated pathway to help restore gut barrier function. We hypothesize that EGCs modulate immune cell recruitment following injury and relay vagal anti-inflammatory signals to resident immune cells in the gut. |
| DOI | 10.1152/ajpgi.00371.2016 |
| PMID | 28082286 |