ヨシダ タクオ
  吉田 拓生
   所属   医学部 医学科(東京女子医科大学病院)
   職種   講師
論文種別 症例報告
言語種別 英語
査読の有無 査読あり
表題 Efficacy of tolvaptan in a patient with right-sided heart failure and renal dysfunction refractory to diuretic therapy.
掲載誌名 正式名:Journal of cardiology cases
略  称:J Cardiol Cases
ISSNコード:18785409/18785409
掲載区分国外
巻・号・頁 9(6),pp.226-229
著者・共著者 Joko Yumiko, Ikemura Nobuhiro, Miyata Kotaro, Shiraishi Yasuyuki, Tanaka Hiroaki, Yoshida Takuo, Ikegami Yukinori, Fuse Jun, Sakamoto Munehisa, Momiyama Yukihiko
発行年月 2014/06
概要 The use of loop diuretics has been shown to deteriorate renal dysfunction and is associated with a poor prognosis in patients with heart failure (HF). Tolvaptan, a vasopressin V2-receptor antagonist, has been reported to be effective in treating HF due to its potent effects of water diuresis and is expected to improve fluid retention without adversely affecting renal function. The present case is a 77-year-old man with pulmonary hypertension associated with chronic pulmonary artery thrombosis and old pulmonary tuberculosis who developed worsening right-sided HF with marked fluid retention and renal dysfunction. In this case, tolvaptan was effective in improving HF without deteriorating the patient's renal dysfunction. <Learning objective: Tolvaptan is effective in treating patients with right-sided heart failure associated with marked fluid retention and renal dysfunction who are refractory to loop diuretics and can improve and control heart failure symptoms without worsening renal dysfunction.>.
DOI 10.1016/j.jccase.2014.02.003
PMID 30534332