KATO Yuka
   Department   Other, Other
   Position  
Article types Original article
Language English
Peer review Peer reviewed
Title Brachial-ankle pulse wave velocity, but not ankle-brachial index, predicts all-cause mortality in patients with diabetes after lower extremity amputation.
Journal Formal name：Journal of diabetes investigation
Abbreviation：J Diabetes Investig
ISSN code：(2040-1124)2040-1116(Linking)
Domestic / ForeginForegin
Volume, Issue, Page 8(2),pp.250-253
Author and coauthor Ikura Kazuki, Hanai Ko, Oka Seiji, Watanabe Makiko, Oda Yuri, Hamada Mariko, Kato Yuka, Shinjyo Takamichi, Uchigata Yasuko
Publication date 2017/03
Summary We examined whether brachial-ankle pulse wave velocity (baPWV) and ankle-brachial pressure index (ABI) are predictors for mortality in diabetic patients after lower extremity amputation. This was an observational historical cohort study of 102 Japanese diabetic patients after first non-traumatic lower extremity amputation, with a mean age of 63 years (standard deviation 12 years). The end-point was all-cause mortality. During the mean follow-up period of 3.3 years, 44 patients reached the end-point. In both univariate and multivariate analyses, baPWV (m/s) (hazard ratio [HR] 1.05 and 1.04, both P < 0.01, respectively), but not ABI (HR 0.38 and 0.89, P = 0.08 and 0.86, respectively), was a significant predictor for the end-point. When baPWV (above or below the median [21.8 m/s]) and ABI (normal [0.9-1.4] or not) were analyzed as categorical variables, the results were similar. In conclusion, baPWV, but not ABI, might be a predictor for all-cause mortality in diabetic patients after lower extremity amputation.
DOI 10.1111/jdi.12554
PMID 27422213