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森 浩輝
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position |
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| Article types | Original article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Sildenafil reduces pulmonary vascular resistance in single ventricular physiology |
| Journal | Formal name：International journal of cardiology Abbreviation：Int J Cardiol ISSN code：18741754/01675273 |
| Domestic / Foregin | Foregin |
| Publisher | Elsevier |
| Volume, Issue, Page | 221,pp.122-127 |
| Author and coauthor | MORI Hiroki†, PARK In-Sam, YAMAGISHI Hiroyuki, NAKAMURA Makoto, ISHIKAWA Shiro, TAKIGIKU Kiyohiro, YASUKOCHI Satoshi, NAKAYAMA Tomotaka, SAJI Tsutomu, NAKANISHI Toshio* |
| Authorship | Lead author |
| Publication date | 2016/10 |
| Summary | Sildenafil reduced PVR in patients with single ventricle physiology. Sildenafil increased exercise capacity and improved NYHA functional class in patients after a Fontan operation. This implies that pulmonary vasodilation is a potential therapeutic target in selected patients with elevated PVR with single ventricle physiology. Long-term clinical significance warrants further study. |
| DOI | 10.1016/j.ijcard.2016.06.322 |
| PMID | 27400308 |