眞部　俊    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Assistant Professor
Article types	Case report
Language	English
Peer review	Peer reviewed
Title	IgG4-Related Tubulointerstitial Nephritis and Lymphadenopathy after Therapy for Malignant Lymphoma.
Journal	Formal name：Internal medicine (Tokyo, Japan) Abbreviation：Intern Med ISSN code：1349-7235(Electronic)0918-2918(Linking)
Volume, Issue, Page	51(10),pp.1221-6
Author and coauthor	Oshima Yasuko†, Usui Ryosuke, Manabe Shun, Hasegawa Naoki, Kakuta Yukio, Nitta Kosaku, Hatano Michiyasu
Publication date	2012/05
Summary	We report a middle-aged Japanese man who had a past history of malignant lymphoma with tubulointerstitial nephritis (TIN) presenting a high serum immunoglobulin G4 (IgG4) concentration and bilateral kidney enlargement and swelling of many lymph nodes. Although lymph node biopsy was not evident of a recurrence of lymphoma, kidney biopsy showed prominent infiltration of IgG4-positive plasma cells in a tubulointerstitial lesion but not in glomeruli. We made a diagnosis of IgG4-related TIN and lymphadenopathy; administration of oral prednisolone improved his physical and laboratory parameters. This is the first report of a case of IgG4-related TIN and lymphadenopathy after therapy for malignant lymphoma.
Document No.	22687794