オオツキ ヒサオ   OOTSUKI Hisao
  大槻 尚男
   所属   医学部 医学科(東京女子医科大学病院)
   職種   特任助教
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Outcomes of Renal Transplant Recipients after Percutaneous Coronary Intervention.
掲載誌名 正式名:The American journal of cardiology
略  称:Am J Cardiol
ISSNコード:0002-9149/1879-1913
掲載区分国外
出版社 Elsevier B.V.
巻・号・頁 in press頁
著者・共著者 NAKAO Masashi†, YAMAGUCHI Junichi*, SATOMI Natsuko, EBIHARA Suguru, TANAKA Kazuki, OOTSUKI Hisao, INAGAKI Yusuke, JUJO Kentaro, ARASHI Hiroyuki, HAGIWARA Nobuhisa
発行年月 2020/02
概要 Renal transplantation (RT) can improve life expectancy in hemodialysis (HD) patients. However, little is known about the outcomes of renal transplant recipients after percutaneous coronary intervention (PCI). This study aimed to elucidate the effect of RT on clinical outcomes after PCI. Renal transplant recipients who underwent PCI from 2002 to 2017 were enrolled. To evaluate the effectiveness of RT, we retrospectively reviewed HD patients who underwent PCI. Propensity-score matching was performed using logistic regression to control for differences in baseline characteristics. The primary outcome was the incidence of major adverse cardiac events. After propensity matching, patients were classified into the RT (n = 50) group and HD (n = 50) group. Kaplan-Meier analysis revealed that the incidence of major adverse cardiac events was significantly lower in the RT group than in the HD group (p < 0.0001). Moreover, RT was associated with a lower risk for all-cause death (odds ratio 0.04; 95% confidence interval 0.002 to 0.03; p = 0.0054) and target vessel revascularization (OR 0.27; 95% CI 0.07 to 0.79; p = 0.015). RT may improve clinical outcomes after PCI, and it is encouraged for HD patients to increase life expectancy and reduce the occurrence of adverse events after PCI. Further research would be warranted to support this finding.
DOI 10.1016/j.amjcard.2020.02.007
PMID 32139159