NAKAJIMA REIKO    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Assistant Professor
Article types	Review article
Language	English
Peer review	Peer reviewed
Title	Pathogenesis and FDG-PET/CT findings of Epstein-Barr virus-related lymphoid neoplasms.
Journal	Formal name：Annals of nuclear medicine Abbreviation：Ann Nucl Med ISSN code：18646433/09147187
Domestic / Foregin	Domestic
Volume, Issue, Page	31(6),pp.425-436
Author and coauthor	Toriihara Akira, Nakajima Reiko, Arai Ayako, Nakadate Masashi, Abe Koichiro, Kubota Kazunori, Tateishi Ukihide
Authorship	2nd author
Publication date	2017/07
Summary	Epstein-Barr virus (EBV) is one of the most common viruses, infecting more than 90% of the adult population worldwide. EBV genome is detected in some lymphoid neoplasms. Not only their histopathological subtypes, but also their backgrounds and their clinical courses are variable. A number of B-cell lymphoproliferative disorders associated with the immunocompromised state are related to EBV infection. The incidences of these disorders have been increasing along with generalization of organ transplantations and use of immunosuppressive treatments. Furthermore, some EBV-positive lymphoma can also occur in immunocompetent patients. While evaluating patients with generalized lymphadenopathy of unknown cause by positron emission tomography/computed tomography with 2-deoxy-2-[18F]fluoro-D-glucose (FDG-PET/CT), the possibility of lymphoid neoplasms should be considered in some patients, and a careful review of the background and previous history of the patients is necessary. In this review article, we describe the pathogenesis of EBV-related lymphoid neoplasms and then present FDG-PET/CT images of representative diseases. In addition, we also present a review of other EBV-related diseases, such as infectious mononucleosis and nasopharyngeal carcinoma.
DOI	10.1007/s12149-017-1180-5
PMID	28497429