Hiroki Ishihara
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Assistant Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Association Between Anesthetic Technique and Survival After Radical Nephroureterectomy: A Propensity Score-matching Study.
Journal Formal name:In vivo (Athens, Greece)
Abbreviation:In Vivo
ISSN code:17917549/0258851X
Domestic / ForeginForegin
Volume, Issue, Page 36(1),pp.458-464
Author and coauthor Ishiyama Yudai, Kondo Tsunenori, Tachibana Hidekazu, Ishihara Hiroki, Nishioki Haruka Ito, Yoshida Kazuhiko, Iizuka Junpei, Tanabe Kazunari, Takagi Toshio
Publication date 2022/01
Summary BACKGROUND/AIM:Whether anesthesia can affect oncological outcomes in urothelial carcinoma of the upper urinary tract undergoing radical nephroureterectomy (RNU) is not clear.PATIENTS AND METHODS:One-hundred an ninety-seven patients who underwent RNU were retrospectively recruited and divided into total intravenous (TIVA, n=90) and volatile inhalation anesthesia (VIA, n=107) groups. A 1:1 propensity score-matching method was employed to minimize selection bias (n=70 each). Cancer-specific (CSS), overall (OS) and metastasis-free (MFS) survival were compared between groups before and after matching.RESULTS:For all survival endpoints, no significant differences were observed between the two study groups, both before (hazard ratio for TIVA: CSS: 0.70, OS: 0.75, MFS: 0.78) and after (hazard ratios for TIV: CSS: 1.21, OS: 0.82, MFS: 0.84) matching.CONCLUSION:With no survival difference observed according to anesthetic technique for RNU, the choice should be based on factors such as accessibility, prevention of side-effects, or costs.
DOI 10.21873/invivo.12725
PMID 34972749