KATOU Naoko    Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine    Position   Assistant Professor
Article types	Original article
Language	English
Peer review	Peer reviewed
Title	Nationwide clinical and epidemiological study of large-vessel vasculitis in Japan in 2017.
Journal	Formal name：Modern rheumatology Abbreviation：Mod Rheumatol ISSN code：14397609/14397595
Volume, Issue, Page	pp.-
Author and coauthor	Konda Naoko, Sakai Ryoko, Saeki Keigo, Matsubara Yuri, Nakamura Yosikazu, Miyamae Takako, Nakaoka Yoshikazu, Harigai Masayoshi
Authorship	Lead author
Publication date	2023/02
Summary	OBJECTIVE:We conducted a nationwide epidemiological study to estimate the number of patients with Takayasu arteritis (TAK) and giant cell arteritis (GCA) in Japan and to describe the clinical characteristics of these patients.METHODS:The first survey was designed to estimate the number of patients with TAK and GCA who were treated at medical institutions in Japan in 2017. The second survey was designed to collect data on the clinical characteristics of the patients who were reported in the first survey.RESULTS:Of the 3,495 institutions selected for the first survey, 1,960 (56.1%) responded. The number of patients with clinically diagnosed TAK and GCA was estimated to be 5,320 (95% confidence interval [CI], 4,810-5,820) and 3,200 (95% CI, 2,830-3,570), respectively. Aortic regurgitation was reported in 35% of patients with TAK, and eye-related comorbidities were observed in 30.4% of patients with GCA. The common carotid and internal carotid arteries were the most frequently involved in patients with TAK (62.7%). Subclavian artery lesions and thoracic or abdominal aorta lesions were reported in 31% and 42.6% of patients with GCA, respectively.CONCLUSIONS:The number of patients with TAK and GCA was estimated simultaneously, and significant differences in clinical characteristics were observed between the two diseases.
DOI	10.1093/mr/road019
PMID	36737863