UEMURA Shuichiro
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Assistant Professor
Article types Case report
Language English
Peer review Non peer reviewed
Title Pancreatic serous cystadenocarcinoma diagnosed with liver metastasis at 7 years after the resection of the primary serous neoplastic lesion.
Journal Formal name：Clinical journal of gastroenterology
Abbreviation：Clin J Gastroenterol
ISSN code：18657265/18657265
Domestic / ForeginForegin
Volume, Issue, Page 15(2),pp.505-512
Author and coauthor TAKAGI Yutaka, HATORI Takashi, ITANO Osamu, SHINODA Masahiro, KATO Atsushi, NITORI Nobuhiro, KATO Fumihiko, KATO Ayu, NAKANO Atsushi, TAMURA Takuya, UEMURA Shuichiro, MIYAZAKI Masaru, AIDA Shinsuke
Publication date 2022/04
Summary Pancreatic serous neoplasms are rare tumors that are usually benign. However, histopathological differentiation between benign (serous cystadenoma) and malignant (serous cystadenocarcinoma) lesions is difficult. We present the case of a patient with pancreatic serous cystadenocarcinoma that was diagnosed with liver metastasis 7 years after the resection of the primary serous neoplastic lesion. A woman in her 60 s was diagnosed with pancreatic serous cystadenoma based on imaging and histopathological examination findings. The tumor was resected, and the patient was followed up every 6 months to monitor tumor progression. At 7 years after the resection of the primary lesion, liver tumors showing marked flare-like contrast enhancements were detected on arterial phase computed tomography findings and on dynamic magnetic resonance imaging findings acquired 60 s after the administration of a contrast agent. Laparoscopic segmental hepatectomy of S4 and S6 was performed to resect these tumors. Histopathological examination revealed that these tumors were metastatic and developed from the primary lesion. Therefore, a diagnosis of serous cystadenocarcinoma was confirmed. The flare-like contrast enhancement around the metastatic liver lesions on computed tomography and dynamic magnetic resonance images may be an indicator of serous cystadenocarcinoma with liver metastasis that could assist in diagnosis.
DOI 10.1007/s12328-021-01570-9
PMID 35013932