ヒグチ　トモアキ   樋口　智昭    所属   医学部 医学科（東京女子医科大学病院）    職種   寄附部門講師
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	A case of Takayasu arteritis complicated with acute pericarditis at initial presentation.
掲載誌名	正式名：Modern rheumatology case reports 略　 称：Mod Rheumatol Case Rep ISSNコード：24725625/24725625
巻・号・頁	7(1),pp.154-159
著者・共著者	Kurokawa Miyu, Higuchi Tomoaki, Hirahara Shinya, Watanabe Kotaro, Yamada Risa, Nakamura Shohei, Takada Hideto, Majima Masako, Motoyama Ryo, Hanaoka Masanori, Katsumata Yasuhiro, Harigai Masayoshi
発行年月	2023/01/03
概要	Takayasu arteritis (TAK) is a rare, large-vessel vasculitis, frequently presenting at approximately 20 years of age. Patients with TAK without characteristic clinical findings are sometimes left undiagnosed and are followed by a fever of unknown origin; delayed diagnosis may lead to irreversible ischaemia and organ damage. Here, we report a case of an 18-year-old woman with TAK complicated by acute pericarditis at initial presentation. She was diagnosed with idiopathic acute pericarditis and treated with non-steroidal anti-inflammatory drugs (NSAIDs). However, the patient's fever and pain in the chest and upper back persisted. On admission to our hospital, magnetic resonance angiography and ultrasonography revealed wall thickening in the common carotid artery, subclavian artery, and aorta, along with vascular narrowing in the celiac, superior mesenteric, and bilateral renal arteries. The patient was diagnosed with TAK and treated with glucocorticoids, including methylprednisolone pulse therapy, and azathioprine. The treatment improved the patient's signs and symptoms, and pericardial effusion decreased. Acute pericarditis is a rare manifestation of TAK, but it is important to differentiate diseases, including TAK in patients with acute pericarditis who fail to respond to 2-3 weeks of conventional therapy with NSAIDs.
DOI	10.1093/mrcr/rxac067
PMID	35993505