髙田 秀人
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Assistant Professor
Article types Case report
Language English
Peer review Peer reviewed
Title Discoid Lupus Erythematosus Complicated with Pregnancy-induced Hemophagocytic Syndrome.
Journal Formal name:Internal medicine (Tokyo, Japan)
Abbreviation:Intern Med
ISSN code:13497235/09182918
Domestic / ForeginDomestic
Volume, Issue, Page 56(12),pp.1581-1583
Author and coauthor Takada Hideto, Kimura Naoki, Yoshihashi-Nakazato Yoko, Kawahata Kimito, Kohsaka Hitoshi
Publication date 2017
Summary A 35-year-old woman with discoid lupus erythematosus (DLE) was admitted at 11 weeks' gestation with a persistent fever. Laboratory studies revealed pancytopenia, elevated liver enzymes, and hyperferritinemia. Bone marrow aspiration confirmed the diagnosis of hemophagocytic syndrome (HPS). She had no findings of infection or active systemic lupus erythematosus. The administration of high-dose corticosteroids resolved the clinical and laboratory findings. She delivered a healthy baby at 35 weeks' gestation. This case suggests that DLE can be a predisposing factor for pregnancy-induced HPS.
DOI 10.2169/internalmedicine.56.8156
PMID 28626188