TAKADA Takuma
Department Graduate School of Medical Science, Graduate School of Medical Science Position |
|
Article types | Original article |
Language | English |
Peer review | Peer reviewed |
Title | Long-term risks for patency loss in patients with hemodialysis after bare self-expandable nitinol stent implantation to femoropopliteal artery occlusive lesions. |
Journal | Formal name:International journal of cardiology Abbreviation:Int J Cardiol ISSN code:18741754/01675273 |
Domestic / Foregin | Foregin |
Volume, Issue, Page | 223,pp.268-275 |
Author and coauthor | Matsumi Junya, Takada Takuma, Moriyama Noriaki, Ochiai Tomoki, Tobita Kazuki, Shishido Koki, Sugitatsu Kazuya, Mizuno Shingo, Yamanaka Futoshi, Murakami Masato, Tanaka Yutaka, Takahashi Saeko, Akasaka Takeshi, Saito Shigeru |
Publication date | 2016/11 |
Summary | BACKGROUND:Although patients receiving hemodialysis (HD+) have significantly different backgrounds, including a history of progressive atherosclerotic disease, compared with those not receiving hemodialysis (HD-), there are no studies evaluating the risks for loss of primary patency (PP) and need for target lesion revascularization (TLR) in HD+ patients following bare self-expandable nitinol stent (BSNS) implantation to femoropopliteal (FP) artery occlusive lesions, after adjusting for differences using propensity score (PS) analysis in observed characteristics between groups.METHODS:We studied 531 limbs of 432 Japanese patients (HD+, n=107; HD-, n=325) who received BSNS implantation to FP lesions between 2004 and 2014. Patients were followed-up for an average of 44.3±33.6months. We compared the long-term results between HD+ and HD- patients using the Cox-proportional hazard model with adjustment for inverse probability treatment weight (IPTW) of PS, which was calculated for covariates with HD as a dependent variable.RESULTS:PP rate in HD+ vs. HD- patients at 9years after the procedure was 19.1% vs. 47.9%, with a freedom from TLR rate of 47.6% vs. 62.9%, respectively. Adjusted HRs in HD+ patients with 95% confidence intervals (CIs) were as follows: loss of PP: HR 1.64, 95% CI 1.052-2.557, P=0.03; TLR: HR 1.862, 95% CI 1.104-3.139, P=0.02.CONCLUSIONS:The present study suggests that HD+ patients have an increased risk for loss of PP and need for TLR after BSNS implantation to FP lesions. |
DOI | 10.1016/j.ijcard.2016.08.235 |
PMID | 27541671 |