TAKADA Takuma
   Department   Research Institutes and Facilities, Research Institutes and Facilities
   Position   Assistant Professor
Article types Original article
Language English
Peer review Peer reviewed
Title Long-term risks for patency loss in patients with hemodialysis after bare self-expandable nitinol stent implantation to femoropopliteal artery occlusive lesions.
Journal Formal name:International journal of cardiology
Abbreviation:Int J Cardiol
ISSN code:18741754/01675273
Domestic / ForeginForegin
Volume, Issue, Page 223,pp.268-275
Author and coauthor Matsumi Junya, Takada Takuma, Moriyama Noriaki, Ochiai Tomoki, Tobita Kazuki, Shishido Koki, Sugitatsu Kazuya, Mizuno Shingo, Yamanaka Futoshi, Murakami Masato, Tanaka Yutaka, Takahashi Saeko, Akasaka Takeshi, Saito Shigeru
Publication date 2016/11
Summary BACKGROUND:Although patients receiving hemodialysis (HD+) have significantly different backgrounds, including a history of progressive atherosclerotic disease, compared with those not receiving hemodialysis (HD-), there are no studies evaluating the risks for loss of primary patency (PP) and need for target lesion revascularization (TLR) in HD+ patients following bare self-expandable nitinol stent (BSNS) implantation to femoropopliteal (FP) artery occlusive lesions, after adjusting for differences using propensity score (PS) analysis in observed characteristics between groups.METHODS:We studied 531 limbs of 432 Japanese patients (HD+, n=107; HD-, n=325) who received BSNS implantation to FP lesions between 2004 and 2014. Patients were followed-up for an average of 44.3±33.6months. We compared the long-term results between HD+ and HD- patients using the Cox-proportional hazard model with adjustment for inverse probability treatment weight (IPTW) of PS, which was calculated for covariates with HD as a dependent variable.RESULTS:PP rate in HD+ vs. HD- patients at 9years after the procedure was 19.1% vs. 47.9%, with a freedom from TLR rate of 47.6% vs. 62.9%, respectively. Adjusted HRs in HD+ patients with 95% confidence intervals (CIs) were as follows: loss of PP: HR 1.64, 95% CI 1.052-2.557, P=0.03; TLR: HR 1.862, 95% CI 1.104-3.139, P=0.02.CONCLUSIONS:The present study suggests that HD+ patients have an increased risk for loss of PP and need for TLR after BSNS implantation to FP lesions.
DOI 10.1016/j.ijcard.2016.08.235
PMID 27541671