SAGAWA Takaomi
   Department   School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine
   Position   Assistant Professor
Article types Case report
Language English
Peer review Peer reviewed
Title Elevated α-Fetoprotein in the Absence of Carcinoma Caused by Relapse of Hepatitis C Viral Infection after Liver Transplantation.
Journal Formal name:ACG case reports journal
Abbreviation:ACG Case Rep J
ISSN code:(2326-3253)2326-3253(Linking)
Volume, Issue, Page 5,pp.e103
Author and coauthor KOGISO Tomomi,SAGAWA Takaomi,KOTERA Yoshihito,EGAWA Hiroto,YAMAMOTO Masakazu,TOKUSHIGE Katsutoshi
Authorship 2nd author
Publication date 2018/12
Summary We report a rare case of marked elevation of α-fetoprotein in the absence of hepatocellular carcinoma caused by a relapse of hepatitis C virus (HCV) infection. A 58-year-old man underwent liver transplantation to treat hepatocellular carcinoma caused by HCV-related liver cirrhosis. The HCV was of genotype 2a, and the ribonucleic acid titer was >8.0 log IU/mL. Direct-acting antiviral drugs were prescribed for 12 weeks; however, the HCV infection relapsed after treatment had ended, and α-fetoprotein levels increased to 8,981 ng/mL. Imaging did not reveal any malignancies. The patient initiated interferon therapy, at which time AFP levels decreased, and the HCV was successfully cleared.
DOI 10.14309/crj.2018.103
PMID 30643846