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SAGAWA Takaomi
Department School of Medicine(Tokyo Women's Medical University Hospital), School of Medicine Position Assistant Professor |
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| Article types | Case report |
| Language | English |
| Peer review | Peer reviewed |
| Title | Elevated α-Fetoprotein in the Absence of Carcinoma Caused by Relapse of Hepatitis C Viral Infection after Liver Transplantation. |
| Journal | Formal name：ACG case reports journal Abbreviation：ACG Case Rep J ISSN code：(2326-3253)2326-3253(Linking) |
| Volume, Issue, Page | 5,pp.e103 |
| Author and coauthor | KOGISO Tomomi,SAGAWA Takaomi,KOTERA Yoshihito,EGAWA Hiroto,YAMAMOTO Masakazu,TOKUSHIGE Katsutoshi |
| Authorship | 2nd author |
| Publication date | 2018/12 |
| Summary | We report a rare case of marked elevation of α-fetoprotein in the absence of hepatocellular carcinoma caused by a relapse of hepatitis C virus (HCV) infection. A 58-year-old man underwent liver transplantation to treat hepatocellular carcinoma caused by HCV-related liver cirrhosis. The HCV was of genotype 2a, and the ribonucleic acid titer was >8.0 log IU/mL. Direct-acting antiviral drugs were prescribed for 12 weeks; however, the HCV infection relapsed after treatment had ended, and α-fetoprotein levels increased to 8,981 ng/mL. Imaging did not reveal any malignancies. The patient initiated interferon therapy, at which time AFP levels decreased, and the HCV was successfully cleared. |
| DOI | 10.14309/crj.2018.103 |
| PMID | 30643846 |