マツオカ　アヤコ   MATSUOKA Ayako   松岡　綾子    所属   医学部 医学科（東京女子医科大学病院）    職種   講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Moyamoya disease complicated by Graves' disease and type 2 diabetes mellitus: report of two cases.
掲載誌名	正式名：Clinical neurology and neurosurgery 略　 称：Clin Neurol Neurosurg ISSNコード：18726968/03038467
掲載区分	国外
巻・号・頁	113(4),pp.325-9
著者・共著者	Sakiko Suzuki, Tetsuryu Mitsuyama, Ayako Horiba, Sayaka Fukushima, Naotake Hashimoto, Takakazu Kawamata
発行年月	2011/05
概要	The pathogenesis of moyamoya disease remains unknown. Examination of diseases concurrent with moyamoya disease may offer a clue to clarify the pathogenesis. Coexistence of moyamoya disease, Graves' disease, and diabetes mellitus is very rare. We present the first cases in the literature. A 38-year-old man with moyamoya disease and a 43-year-old woman with quasi-moyamoya disease, both concurrent with Graves' disease and type 2 diabetes mellitus, are presented. Both patients underwent antithyroid therapy and revascularization. After normalization of thyroid hormones level and blood glucose level followed by revascularization, the symptoms of cerebral ischemia were improved. The common etiological factors of these diseases are discussed. Genetic and autoimmune factor appeared to be involved in the pathogenesis of the three diseases, which may suggest that these factors play important roles in the pathogenesis of moyamoya disease. Further studies are required to define the pathogenesis of moyamoya disease, especially in cases with comorbidities as in the present patients.
DOI	10.1016/j.clineuro.2010.11.022
PMID	21215511