ハヤシ　ヨシロウ   HAYASHI Yoshirou   林　淑朗    所属   医学部 医学科（東京女子医科大学病院）    職種   客員教授
論文種別	原著
言語種別	英語
査読の有無	査読なし
表題	Contamination of Blood Cultures Drawn From Arterial Catheters Versus Venipuncture or Venous Catheters in Critically Ill Patients: A Systematic Review and Meta-analysis.
掲載誌名	正式名：Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 略　 称：Clin Infect Dis ISSNコード：15376591/10584838
掲載区分	国外
巻・号・頁	82(3),pp.446-452
著者・共著者	Takatoshi Koroki†, Motoki Fujii, Yuki Kotani*, Takahiko Yaguchi, Taisuke Shibata, Chihiro Hirata, Naoki Okawa, Koshi Ota, Mayuko Tonai, Toshiyuki Karumai, Yuki Kataoka, Yoshiro Hayashi
発行年月	2026/03
概要	BACKGROUND:Arterial catheter-drawn blood culture sampling may reduce patient discomfort and healthcare providers' workload. Guidelines discourage transcatheter blood culture collection due to contamination risks, mainly derived from data on venous catheter-drawn cultures. However, contamination rates of arterial catheter-drawn cultures have not been comprehensively evaluated compared with venipuncture- or venous catheter-drawn cultures.METHODS:We searched PubMed, Embase, and the Cochrane Library from inception through 5 December 2023, for studies comparing arterial catheter-drawn blood cultures with venipuncture- or venous catheter-drawn blood cultures. The primary outcome was blood culture contamination rate. We performed a random-effects meta-analysis and evaluated the certainty of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology.RESULTS:We included 6 studies involving 8533 blood cultures. When comparing arterial catheter- with venipuncture-drawn cultures, the crude contamination rates were 28/1355 (2.1%) and 103/4539 (2.3%), respectively. Arterial catheter-drawn cultures may not increase contamination rates compared to venipuncture-drawn cultures (risk difference [RD], 0.01 [95% confidence interval {CI}, -.01 to .02]; low certainty). When comparing arterial catheter- with venous catheter-drawn cultures, the crude contamination rates were 15/489 (3.1%) and 211/2639 (8.0%), respectively. Compared to venous catheter-drawn cultures, arterial catheter-drawn cultures may have lower contamination rates (RD, -0.05 [95% CI, -.11 to .01]; low certainty).CONCLUSIONS:In critically ill patients, arterial catheter-drawn blood cultures may have contamination rates comparable to venipuncture-drawn cultures and potentially lower than venous catheter-drawn cultures.CLINICAL TRIALS REGISTRATION:PROSPERO (CRD42023486227).
DOI	10.1093/cid/ciaf260
PMID	40394840