ホシノ　ジュンイチ   Hoshino Junichi   星野　純一    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	原著
言語種別	英語
査読の有無	査読なし
表題	Complete Remission After Percutaneous Renal Artery Angioplasty for Focal Segmental Glomerulosclerosis due to Takayasu Disease: A Case Report.
掲載誌名	正式名：Kidney medicine 略　 称：Kidney Med ISSNコード：25900595/25900595
掲載区分	国外
巻・号・頁	8(3),pp.101251
著者・共著者	Ushio Yusuke, Manabe Shun, Nakai Anna, Seki Momoko, Makabe Shiho, Kobayashi Shizuka, Kawaguchi Yuki, Kataoka Hiroshi, Ito Naoko, Taneda Sekiko, Honda Kazuho, Hoshino Junichi
担当区分	最終著者
発行年月	2026/03
概要	Renal artery stenosis is a common complication of Takayasu disease; however, the presence of nephrotic syndrome is rare. Percutaneous transluminal renal angioplasty (PTRA) is performed for renal artery stenosis; however, its efficacy is unclear for renal artery stenosis complicated with nephrotic syndrome. This is a case report of Takayasu disease in an 18-year-old woman with no relevant medical history. Magnetic resonance angiography revealed bilateral renal artery stenosis, and nephrotic syndrome was noted. Focal segmental glomerulosclerosis was diagnosed based on renal biopsy. As atrophy was observed in the right kidney, PTRA was performed for the left renal artery stenosis. Urine protein levels decreased subsequently, leading to remission. Renal artery stenosis may commonly occur due to Takayasu disease; however, the resulting accentuation of the renin-angiotensin-aldosterone cascade and increased intraglomerular pressure may cause focal segmental glomerulosclerosis. PTRA may induce remission if renal dysfunction is mild, and it should be performed as early as possible.
DOI	10.1016/j.xkme.2026.101251
PMID	41767684