ハシモト　ヒロツグ   HASHIMOTO Hirotsugu   橋本　浩次    所属   医学部 医学科    職種   准教授
論文種別	総説
言語種別	英語
査読の有無	査読あり
招待の有無	招待あり
表題	Solitary Pulmonary Capillary Hemangioma: Recognition, Clinicopathological Characteristics, and Recent Advances
掲載誌名	正式名：Pathology International 略　 称：Pathol Int ISSNコード：14401827/13205463
掲載区分	国外
巻・号・頁	76(2),pp.e70090
著者・共著者	Hashimoto Hirotsugu†*
担当区分	筆頭著者,責任著者
発行年月	2026/02
概要	Solitary pulmonary capillary hemangioma (SPCH) is a rare, benign nodular lesion composed of proliferating capillaries in the lung. While pulmonary capillary hemangiomatosis-characterized by diffuse or patchy capillary proliferation in the lung leading to pulmonary hypertension and eventually fatal outcomes-has been recognized since 1978, the concept of solitary capillary hemangioma of the lung began to emerge in 2000 and has been increasingly recognized through subsequent reports. SPCH typically presents as a solitary nodule < 20 mm in diameter, often appearing as a ground-glass nodule on computed tomography. These features can closely mimic early-stage lung adenocarcinoma, posing a diagnostic challenge. In addition, SPCH is often difficult to palpate during surgery, which occasionally complicates intraoperative management. This review outlines the historical background of SPCH and summarizes its clinicoradiological, surgical (including intraoperative diagnosis), pathological (gross appearance and histopathological findings), and molecular characteristics. In particular, a literature review of previous studies, together with our own cases, highlights its distinguishing clinicoradiological features. Furthermore, SPCH is discussed in the broader context of pulmonary vascular tumors, and future directions for research and clinical practice are proposed.
DOI	10.1111/pin.70090
PMID	41653127