タカダ　タクマ   TAKADA Takuma   髙田　卓磨    所属   医学研究科 医学研究科 (医学部医学科をご参照ください)    職種   非常勤講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Impact of the Balloon Pulmonary Angioplasty on the Diagnosis of Chronic Thromboembolic Pulmonary Hypertension: From the COMMAND VTE Registry-2.
掲載誌名	正式名：Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 略　 称：Catheter Cardiovasc Interv ISSNコード：1522726X/15221946
掲載区分	国外
巻・号・頁	106(4),pp.2753-2762
著者・共著者	Tatsunori Noto, Nobutaka Ikeda, Yugo Yamashita, Takeshi Morimoto, Ryuki Chatani, Kazuhisa Kaneda, Yuji Nishimoto, Yohei Kobayashi, Satoshi Ikeda, Kitae Kim, Moriaki Inoko, Toru Takase, Shuhei Tsuji, Maki Oi, Takuma Takada, Kazunori Otsui, Jiro Sakamoto, Yoshito Ogihara, Takeshi Inoue, Shunsuke Usami, Po-Min Chen, Kiyonori Togi, Norimichi Koitabashi, Seiichi Hiramori, Kosuke Doi, Hiroshi Mabuchi, Yoshiaki Tsuyuki, Koichiro Murata, Kensuke Takabayashi, Hisato Nakai, Daisuke Sueta, Wataru Shioyama, Tomohiro Dohke, Takeshi Kimura,
発行年月	2025/10
概要	BACKGROUND:Chronic thromboembolic pulmonary hypertension (CTEPH) is the most serious long-term complication of acute pulmonary embolism (PE). Balloon pulmonary angioplasty (BPA) has been an effective treatment for improving the prognosis of CTEPH patients.AIMS:This study aimed to evaluate the impact of BPA at each institution on the rate of CTEPH diagnosis based on the observations suggesting that the emergence of effective treatments could draw attention to targeted diseases.METHODS:The COMMAND VTE Registry-2 is a multicenter, retrospective cohort study of 5197 patients diagnosed with venous thromboembolism (VTE) at 31 medical centers in Japan. The study included 2787 patients with acute PE, who were divided into the BPA-capable facility group (BPA centers) and the non-BPA-capable facility group (non-BPA centers). We investigated the difference in the rate of CTEPH diagnosis after acute PE between the two groups.RESULTS:Among patients with acute PE, 723 patients (25.9%) and 2064 patients (74.1%) were diagnosed at BPA centers and non-BPA centers, respectively. There were 48 patients who were diagnosed with CTEPH, with a median follow-up period of 747 days. The cumulative 3-year incidence of CTEPH diagnosis was 5.0% in the BPA centers and 1.4% in the non-BPA centers (crude hazard ratio [HR]: 3.80; 95% CI: 2.15-6.72; p < 0.001).CONCLUSION:The cumulative 3-year incidence of CTEPH diagnosis after acute PE was significantly greater in BPA centers than in non-BPA centers, which suggests the importance of appropriate awareness of CTEPH and BPA.
DOI	10.1002/ccd.70130
PMID	40856094