|
タカハシ ヒロノブ
TAKAHASHI Hironobu
高橋 宏信 所属 医学研究科 医学研究科 (医学部医学科をご参照ください) 職種 講師 |
|
| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Anisotropic Mesenchymal Stem Cell Sheet Composed of Adipose-Tissue- and Umbilical-Cord-Derived Mesenchymal Stem Cells. |
| 掲載誌名 | 正式名：Biological & pharmaceutical bulletin 略 称：Biol Pharm Bull ISSNコード：13475215/09186158 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 48(7),pp.1107-1110 |
| 著者・共著者 | NAGASE Kenichi†*, KURAMOCHI Hasumi, TAKAHASHI Hironobu* |
| 担当区分 | 責任著者 |
| 発行年月 | 2025 |
| 概要 | Mesenchymal stem cell (MSC) sheet therapies are effective in treating intractable diseases. Aligned and oriented bone-marrow-derived MSC sheets have been developed using stripe-patterned thermoresponsive cell culture dishes to increase the effectiveness of MSC therapies compared with unaligned MSC sheets. However, adipose-tissue- and umbilical-cord-derived MSCs (ADMSCs and UCMSCs, respectively) have not yet been used for preparing aligned cell sheets. Therefore, we prepared aligned cell sheets comprising ADMSCs and UCMSCs. We produced a patterned cell culture dish by modifying polyacrylamide into a striped pattern on a commercially available poly(N-isopropylacrylamide)-modified dish. Aligned cell sheets comprising ADMSCs and UCMSCs were successfully prepared in these culture dishes. |
| DOI | 10.1248/bpb.b25-00364 |
| PMID | 40721369 |