アカバ トモヒロ   AKABA Tomohiro
  赤羽 朋博
   所属   医学部 医学科(東京女子医科大学病院)
   職種   助教
論文種別 原著
言語種別 英語
査読の有無 査読なし
表題 Expert consensus on cancer treatment-related lung injury.
掲載誌名 正式名:Journal of thoracic disease
略  称:J Thorac Dis
ISSNコード:20721439/20721439
掲載区分国外
巻・号・頁 17(4),pp.1844-1875
著者・共著者 X Lin†, H Guo, W Zhao, M Li, G Lin, Q Chu, E Chen, L Chen, R Chen, T Chu, H Deng, Y Deng, H Dong, W Dong, Y Dong, W Fang, X Gan, L Gong, Y Gu, Q Han, Y Hao, Y He, C Hu, J Hu, Y Hu, Y Jiang, Y Jin, F Lan, W Li, W Li, W Liang, A Liu, D Liu, M Liu, M Liu, Z Liu, Z Liu, Q Luo, L Miao, C Mu, P Pan, P Peng, J Qin, Y Qin, Po Shen, M Shi, Y Song, C Su, J Su, X Su, X Tan, K Tang, X Tang, P Tian, B Wang, H Wang, K Wang, M Wang, Q Wang, W Wang, Z Wang, D Wu, F Xu, Y Xu, C Xu, Z Xie, X Xie, B Yang, M Yang, F Ye, X Ye, Z Yu, J Zhang, J Zhang, X Zhang, F Zhao, X Zheng, B Zhu, Z Zhu, J Zhou, J Zhou, M Zhou, Q Zhou, Z Zou, B Kidane, E Bignami, F Sakamaki, G Roviello, H Taniguchi, K Jeon, L Saric, M Ariza-Prota, NM La-Beck, N Kanaji, S Watanabe, T Shukuya, T Akaba, TL Leong, W Gesierich, Y Koga, Y Tanino, Y Uehara, S Li, R Chen, C Zhou
発行年月 2025/04
概要 BACKGROUND:Although advancements in cancer therapies have substantially improved the survival of cancer patients, these treatments may also result in acute or chronic lung injury. Cancer treatment-related lung injury (CTLI) presents with a diverse array of clinical manifestations and can involve multiple sites. Due to the lack of specific diagnostic protocols, CTLI can deteriorate rapidly and may be life-threatening if not promptly addressed. Unfortunately, there is no universally accepted consensus document on the diagnosis and management of CTLI.METHODS:A multidisciplinary panel comprising experts from respiratory and critical care medicine, oncology, radiation oncology, thoracic surgery, radiology, pathology, infectious diseases, pharmacy, and rehabilitation medicine participated in this consensus development. Through a systematic literature review and detailed panel discussions, the team formulated nine key recommendations.RESULTS:This consensus document addresses the concept, epidemiology, pathogenesis, risk factors, diagnostic approach, evaluation workflow, management strategies, differential diagnosis, type-specific management and clinical staging of CTLI. Emphasis is placed on raising awareness among clinicians and therapeutic practices through comprehensive guidelines.CONCLUSIONS:The consensus provides a detailed diagnostic protocol for CTLI and introduces a structured management framework based on grading, typing, and staging. It highlights the critical role of multidisciplinary team (MDT) collaboration and emphasizes the need for individualized, whole-process patient care strategies to optimize clinical outcomes.
DOI 10.21037/jtd-2025-292
PMID 40400937