イカリ カツノリ   IKARI Katsunori
  猪狩 勝則
   所属   医学部 医学科(東京女子医科大学病院)
   職種   教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Preoperative computer tomography scans can accurately evaluate tibial bone mineral density for selecting bone fixation in total knee arthroplasty.
掲載誌名 正式名:Journal of ISAKOS : joint disorders & orthopaedic sports medicine
略  称:J ISAKOS
ISSNコード:20597762/20597754
掲載区分国外
巻・号・頁 12,pp.100894
著者・共著者 Yoshinori Mikashima, Hitoshi Imamura, Koichiro Yano, Katsunori Ikari, Hiroshi Takagi, Ken Okazaki
発行年月 2025/06
概要 INTRODUCTION/OBJECTIVE:The mechanical quality of bone at the proximal tibia is an important factor for the success of cementless total knee arthroplasty (TKA). The purpose of this study was to evaluate the relationship between preoperative bone mineral density (BMD) at the tibial resection level (tibial BMD) using computed tomography (CT) and intraoperative cancellous bone durability (ICBD) in TKA.METHODS:All consecutive cemented and cementless TKAs performed by a single surgeon between April 2024 and October 2024 were evaluated. All patients were examined preoperatively for tibial BMD via CT, hip BMD via dual-energy X-ray absorptiometry. A block of cancellous bone with a diameter of 10 ​mm and a height of 10 ​mm was harvested at the center of the tibia. The fixation method was selected intraoperatively according to the macroscopically evaluated bone quality. Using a pusher tension gauge and a metal measure, the force required to compress the harvested bone from 10 ​mm to 5 ​mm was measured and defined as ICBD. Pearson product-moment correlations were calculated to assess the relationships between tibial and hip BMD and ICBD.RESULTS:A consecutive series of 74 TKAs were included. There were 50 cementless fixations and 24 cemented fixations. Tibial BMD, hip BMD and mean ICBD were significantly greater in the cementless group than in the cemented group (tibial BMD: 70.3 ± 26.2 vs 37.5 ± 14.4, and hip BMD: 87.3 ± 11.8 vs 65.6 ± 10.5, ICBD: 85.6 ± 35.6 vs 49.8 ± 18.1, respectively, P < 0.01). The cut-off value of tibial BMD indicating a cementless prosthesis was 46.4 HA/cm3. There was a very strong correlation between tibial BMD and ICBD (r = 0.88, P < 0.01) and a strong correlation between hip BMD and ICBD(r = 0.62, P < 0.01).CONCLUSION:This study is the first report to focus on the relationships between CT-based tibial BMD and the actual bone quality of the proximal tibia . Assessment of bone quality via CT is accurate, relatively simple, and potentially useful for determining whether cementless fixation in TKA is indicated. For cementless fixation, 46.4 HA/cm3 and 55.7 N were found as tibial BMD and ICBD cut-off values.LEVEL OF EVIDENCE:Retrospective cohort study, Level Ⅳ.
DOI 10.1016/j.jisako.2025.100894
PMID 40334842