イシガキ　ケイコ   ISHIGAKI Keiko   石垣　景子    所属   医学部 医学科（東京女子医科大学病院）    職種   准教授
論文種別	総説
言語種別	英語
査読の有無	査読なし
表題	[Treatment of Juvenile Myasthenia Gravis]
掲載誌名	正式名：BRAIN and NERVE: 神経研究の進歩 ISSNコード：18816096
掲載区分	国内
巻・号・頁	76(1),pp.21-26
著者・共著者	ISHIGAKI Keiko
発行年月	2024/06
概要	The pathogenesis of juvenile myasthenia gravis is similar to that of adult-onset cases, but does differ significantly in that it is predominantly ocular type, has a low antibody-positive rate, a low thymoma complication rate, and a high remission rate. The evidence for the adult treatment strategy of low-dose steroids and fast-acting treatment is insufficient in children, and the safety of immunosuppressive drugs has not been established. Steroid use in children in particular requires caution due to the risk of growth retardation, and while lower doses are desirable, the efficacy of lower doses has not been as fully investigated as in adults. Conversely, experience has shown that the use of adequate doses of steroids results in high remission rates, and there is currently no rationale for recommending lower doses.
DOI	10.11477/mf.1416202553.
PMID	38191135