ワカバヤシ　ヒデタカ   WAKABAYASHI Hidetaka   若林　秀隆    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Sex differences in sarcopenia prevalence and muscle-related outcomes among post-stroke inpatients.
掲載誌名	正式名：European geriatric medicine 略　 称：Eur Geriatr Med ISSNコード：18787649/18787649
掲載区分	国外
巻・号・頁	pp.1
著者・共著者	Yoshimura Yoshihiro, Wakabayashi Hidetaka, Nagano Fumihiko, Matsumoto Ayaka, Shimazu Sayuri, Shiraishi Ai, Kido Yoshifumi, Bise Takahiro, Hamada Takenori, Yoneda Kouki
担当区分	2nd著者
発行年月	2025/03
概要	BACKGROUND:Sex differences in sarcopenia prevalence and recovery patterns among post-stroke patients remain poorly understood. This study aimed to investigate sex differences in sarcopenia prevalence, improvement rates, and changes in muscle-related indices among post-stroke patients in rehabilitation settings.METHODS:A retrospective cohort study was conducted at a post-acute rehabilitation hospital. Sarcopenia was diagnosed using the Asian Working Group for Sarcopenia 2019 criteria. The primary outcomes were sarcopenia status and muscle-related indices (handgrip strength and skeletal muscle mass index) at discharge. Propensity score-adjusted logistic regression analysis was performed to examine the association between sex and non-sarcopenia at discharge.RESULTS:A total of 598 patients (274 women) with a mean age of 71.6 years were analyzed. Women showed higher sarcopenia prevalence at admission compared to men (47.4% vs 34.2%, p = 0.001). After adjusting for confounders, male sex was positively associated with non-sarcopenia at discharge (OR 1.046, 95% CI 1.009-1.104, p < 0.001) and greater improvements in handgrip strength (B = 1.93, p = 0.031) and skeletal muscle mass index (B = 0.322, p = 0.019).CONCLUSION:This study revealed significant sex differences in sarcopenia among post-stroke rehabilitation patients. While women showed higher sarcopenia prevalence at admission, men demonstrated better improvements in muscle-related outcomes.
DOI	10.1007/s41999-025-01186-z
PMID	40123027