コンドウ　ミツコ   KONDOU Mitsuko   近藤　光子    所属   医学部 医学科（東京女子医科大学病院）    職種   客員教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	IgG4-related pleural disease diagnosed by thoracoscopic pleural biopsy: A case report.
掲載誌名	正式名：Respirology case reports 略　 称：Respirol Case Rep ISSNコード：20513380/20513380
掲載区分	国外
巻・号・頁	12(8),pp.e01442
著者・共著者	Miyoshi Azusa†, Katsura Hideki, Akaba Tomohiro, Kondo Mitsuko, Tagaya Etsuko
発行年月	2024/08
概要	Here we report a rare case of immunoglobulin G4 (IgG4)-related pleural disease diagnosed using a thoracoscopic pleural biopsy. A 66-year-old man was admitted to our hospital with right-dominant bilateral pleural effusions and gradually worsening dyspnoea. Chest radiographs revealed right-dominant pleural effusions, while chest computed tomography showed bilateral pleural effusions without parenchymal lesions. Although the bilateral pleural effusions were exudative with an increased number of lymphocytes, the definitive diagnosis was initially elusive. High IgG4 levels in the serum and pleural effusions were observed. A pathological evaluation of a right pleural biopsy specimen collected via video-assisted thoracoscopic surgery showed fibrosis-associated lymphoplasmacytic infiltration, 45-60 IgG4-positive plasma cells per high-power field, and an IgG4/immunoglobulin G ratio of 40%. Consequently, the patient was diagnosed with IgG4-related pleural disease. The bilateral pleural effusions improved after corticosteroid therapy.
DOI	10.1002/rcr2.1442
PMID	39086726