クロダ　ハジメ   KURODA Hajime   黒田　一    所属   医学部 医学科（附属足立医療センター）    職種   教授
論文種別	総説
言語種別	英語
査読の有無	査読あり
表題	Classification of Fibroepithelial Lesions of the Breast in Core Needle Biopsy With Implications for Further Management.
掲載誌名	正式名：Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 略　 称：Mod Pathol ISSNコード：15300285/08933952
掲載区分	国外
巻・号・頁	38(5),pp.100734
著者・共著者	Rakha Emad A†*, Quinn Cecily, Raymond Wendy, Allison Kimberly H, Badve Sunil S, Brogi Edi, Callagy Grace, Charafe-Jauffret Emmanuelle, Chen Chih Jung, Chen Yunn-Yi, Collins Laura C, Cserni Gábor, Djerroudi Lounes, Jaffer Shabnam, Foschini Maria Pia, Gobbi Helenice, Gudi Mihir, Harada Oi, Kulka Janina, Kuroda Hajime, Lakhani Sunil R, Li Xiaoxian, Moriya Takuya, O'Toole Sandra A, Pinder Sarah E, Provenzano Elena, Sahin Aysegul A, Schmitt Fernando, Shaaban Abeer M, Siziopikou Kalliopi P, Tang Ping, Tse Gary M, Varga Zsuzsanna, Vincent-Salomon Anne, Wen Hannah, Yamaguchi Rin, Yang Wentao, Fox Stephen B, Schnitt Stuart J, Ellis Ian O, Tan Puay Hoon
発行年月	2025/02
概要	Fibroepithelial lesions (FELs) of the breast represent a diverse group of biphasic tumors with varying morphologies and clinical behavior. The classification of FELs is mainly based on a constellation of diagnostic criteria, and intralesional heterogeneity is not uncommon. Therefore, reporting FELs in a core needle biopsy (CNB) with limited tissue material can be challenging as not all the features may be represented for assessment. Differentiating a classic fibroadenoma from a well-sampled phyllodes tumor (PT) is generally straightforward. However, cellular fibroadenoma, morphologically heterogeneous benign PT, and myoid hamartoma can overlap histologically. Accurate grading of PT is also challenging on CNB and carries significant management implications. In this article, we provide an overview and propose a pragmatic approach to reporting FELs on CNB, particularly for lesions with overlapping features. Guidance using the UK/European "B" classification of FELs alongside descriptive reporting of the various lesions, is also presented to aid in management decisions.
DOI	10.1016/j.modpat.2025.100734
PMID	39947480