イイダ　トモヒロ   IIDA Tomohiro   飯田　知弘    所属   医学部 医学科（東京女子医科大学病院）    職種   客員教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Impact of perioperative cerebral blood flow evaluation using arterial spin labeling in a patient undergoing carotid artery stenting.
掲載誌名	正式名：Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 略　 称：J Clin Neurosci ISSNコード：15322653/09675868
掲載区分	国外
巻・号・頁	132,pp.110974
著者・共著者	Iida Tomohiro, Yamashita Kentaro, Kato Yuki, Yamamoto Rikiyoshi, Uematsu Koudai, Kuroda Tatsuya, Murase Satoru, Izumo Tsuyoshi
発行年月	2025/02
概要	BACKGROUND:Hyperperfusion syndrome (HPS) is one of the most serious complications after carotid artery stenting (CAS). Arterial spin labeling (ASL) is a noninvasive method for assessing cerebral perfusion. This study aimed to evaluate the utility of ASL compared to that of SPECT in evaluating changes in intracranial blood flow during the perioperative period of CAS.METHODS:We retrospectively reviewed prospectively collected data from 49 cases of CAS conducted for symptomatic and asymptomatic carotid artery stenosis. We calculated the relative cerebral blood flow (rCBF) from ASL (post labeling delay [PLD] of 1500 ms and 2500 ms) and SPECT, both pre- and post-CAS. Cerebrovascular reactivity (CVR) was assessed using SPECT with an acetazolamide challenge. We defined the change rate from PLD 1500 ms to 2500 ms before CAS as ΔrASL.RESULTS:Hyperperfusion phenomenon was observed in four cases (8.2 %), with one case (2.0 %) resulting in cerebral hemorrhage and diagnosed as HPS. Positive correlations were noted between ASL and SPECT at both pre- and post-CAS (r = 0.42-0.65, p < 0.01). A negative correlation was found between ΔrASL obtained from the two PLDs before CAS and CVR (r=-0.41, p < 0.01).CONCLUSIONS:ASL using two PLDs is a useful method for evaluating changes in CBF during the perioperative period of CAS.
DOI	10.1016/j.jocn.2024.110974
PMID	39675211