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フルイチ ヨシヒロ
FURUICHI Yoshihiro
古市 好宏 所属 医学部 医学科（附属足立医療センター） 職種 准教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Esophageal Varices as an Independent Predictor of Fatal Outcomes after Balloon-Occluded Retrograde Transvenous Obliteration in Patients with Hepatic Encephalopathy. |
| 掲載誌名 | 正式名：Digestive diseases (Basel, Switzerland) 略 称：Dig Dis ISSNコード：14219875/02572753 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 42(6),pp.583-592 |
| 国際共著 | 国際共著 |
| 著者・共著者 | Iwasaki Shuichiro, Uojima Haruki, Sakita Shinya, Masuda Sakue, Kubota Kousuke, Fujikawa Tomoaki, Okubo Tomomi, Setsu Toru, Itokawa Norio, Furuichi Yoshihiro, Arase Yoshitaka, Tukiyama Toshiki, Fujii Kaoru, Hidaka Hisashi, Atsukawa Masanori, Kagawa Tatehiro, Kako Makoto, Terai Shuji, Kusano Chika |
| 発行年月 | 2024 |
| 概要 | INTRODUCTION:The objective of this study was to evaluate esophageal varices (EVs) as predictors of poor prognosis with low tolerability after balloon-occluded retrograde transvenous obliteration (BRTO) in patients with overt hepatic encephalopathy (HE).METHODS:This study retrospectively enrolled 107 patients who underwent BRTO for uncontrollable overt HE. The enrolled patients were divided into two groups based on the presence of EVs using propensity matching. The present study assessed the technical success rate and safety of BRTO in both the groups. Further, the event-free survival, HE-free survival, and the overall survival (OS) were compared between the two groups. Event-free survival was defined as the time period during which the patients did not developed complications related to portal hypertension, including EVs, hepatic ascites, and portal vein thrombosis.RESULTS:After propensity matching, the EV and non-EV groups had 37 and 36 patients, respectively. Only 1 patient experienced an unsuccessful procedure in the EV group. Procedure-related adverse events in the EV group and non-EV group occurred in 11 and 7 patients, respectively (p = 0.417). The event-free survival after BRTO in the EV and non-EV group were 1,283 (95% CI: 798-1,767) days and 2,257 (1,722-2,792) days, respectively. Event-free survival was significantly worse in the EV group than in the non-EV group (p = 0.014). Furthermore, the EV group experienced worse OS than the non-EV group (p = 0.001 and p < 0.001, respectively).CONCLUSIONS:The presence of EVs could potentially be associated with a higher risk of adverse outcomes or mortality after BRTO treatment in individuals with HE. |
| DOI | 10.1159/000541660 |
| PMID | 39348798 |