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サイトウ サトシ
Saitou Satoshi
斉藤 聡志 所属 医学部 医学科（東京女子医科大学病院） 職種 助教 |
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| 論文種別 | 症例報告 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Chronic Inflammatory Demyelinating Polyradiculoneuropathy with Diplopia Caused by an Alternative Coronavirus Disease 2019 Vaccine. |
| 掲載誌名 | 正式名：Case reports in neurological medicine 略 称：Case Rep Neurol Med ISSNコード：20906668/20906676 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 2024,pp.8584482 |
| 著者・共著者 | Saito Satoshi, Iijima Mutsumi, Seki Misa, Shimomura Ayato, Kitagawa Kazuo |
| 担当区分 | 筆頭著者 |
| 発行年月 | 2024 |
| 概要 | The etiology of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) remains elusive and is believed to involve multiple contributing factors. There have been cases linking CIDP to the coronavirus disease 2019 (COVID-19) mRNA vaccine. However, there are no documented instances following alternative vaccines. We report a case of a 48-year-old woman, previously vaccinated with Pfizer-BioNTech's COVID-19 vaccine (BNT162b2), who subsequently received the Moderna mRNA-1273 vaccine. Within 2 days postvaccination, she developed diplopia and numbness in the lower limbs' distal extremities. Cerebrospinal fluid analysis exhibited protein-cell dissociation, while F-wave studies showed demyelinating activity in the bilateral tibial nerves. Given the disease's progressive nature, the patient was presumed to have CIDP and commenced steroid pulse therapy and intravenous immunoglobulin therapy. The onset of CIDP may be associated with variations in mRNA sequences and vaccine constituents. |
| DOI | 10.1155/2024/8584482 |
| PMID | 38939233 |