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シンカワ タケシ
SHINKAWA Takeshi
新川 武史 所属 医学部 医学科（東京女子医科大学病院） 職種 教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読なし |
| 表題 | Long-term Outcomes of Surgical Repair for Corrected Transposition of the Great Arteries. |
| 掲載誌名 | 正式名：The Annals of thoracic surgery 略 称：Ann Thorac Surg ISSNコード：15526259/00034975 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 118(6),pp.1279-1287 |
| 著者・共著者 | Yoshida Hisashi†, Shinkawa Takeshi, Yamagata Akiko, Furuta Akihisa, Niinami Hiroshi |
| 発行年月 | 2024/12 |
| 概要 | BACKGROUND:This study investigated the long-term outcomes of physiological and anatomical repair for corrected transposition of the great arteries and double-outlet right ventricle with discordant atrioventricular connection.METHODS:This single-center retrospective study included 146 patients who underwent biventricular repair of corrected transposition of the great arteries or double-outlet right ventricle with discordant atrioventricular connections from 1972 to 2023. Survival rate, freedom from reoperation, New York Heart Association (NYHA) Functional Classification, and incidence of systemic ventricular dysfunction in the long-term were compared between physiological repair (PR) and anatomical repair (AR) groups.RESULTS:The PR group consisted of 55 patients, with median age at repair of 10.3 years. Thirty-one patients underwent conventional Rastelli procedure, and 24 patients underwent atrial and/or ventricular septal defect closure. The AR group consisted of 91 patients, with median age at repair of 5.8 years. Seventy-two patients underwent atrial switch plus Rastelli procedure and 19 patients underwent atrial plus arterial switch operation. The 30-year survival was 63.5% in the PR group and 72.3% in the AR group (P = .448). The 30-year freedom from reoperation was 71.9% in the PR group and 62.2% in the AR group (P = .220). There was a significant difference in the incidence of systemic ventricular dysfunction between the groups (87.5% in the PR group and 35.3% in the AR group, P < .001) and in the NYHA classification of long-term survivors (mean NYHA class of 1.9 in the PR group and 1.5 in the AR group, P = .009).CONCLUSIONS:The systemic ventricular function and general status in the long-term were significantly better in AR patients, suggesting the potential advantage of AR. |
| DOI | 10.1016/j.athoracsur.2024.06.010 |
| PMID | 38936589 |