オマタ　タク   Omata Taku   小俣　卓    所属   医学部 医学科（附属八千代医療センター）    職種   准教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Acute disseminated encephalomyelitis: the time until diagnosis and its subsequent course in children.
掲載誌名	正式名：Journal of child neurology 略　 称：J Child Neurol ISSNコード：17088283/08830738
掲載区分	国外
巻・号・頁	29(1),pp.28-30
著者・共著者	Omata Taku, Fujii Katsunori, Tanabe Yuzo, Arai Hidee, Motojima Toshino
担当区分	筆頭著者,責任著者
発行年月	2014/01
概要	Acute disseminated encephalomyelitis has an acute onset followed by improvement over several weeks. However, some cases require more time for a definitive diagnosis after protracted psychiatric or nonspecific symptoms. The authors investigated the time from onset to definitive diagnosis, subsequent course of treatment, and outcomes in 7 children with acute disseminated encephalomyelitis treated at the authors' hospital. The mean duration of illness before definitive diagnosis was 20.7 days (range: 2-50 days). Steroid pulse therapy was performed in all cases, and rapid improvements were observed; the mean duration from treatment initiation to hospital discharge was 8.6 days (range: 4-14 days). None of the cases showed neurological sequelae. Although this study investigated a small number of patients, its results suggest that time to diagnosis is often longer in children than in adults, and even in cases of delayed treatment, response to steroid pulse therapy is good and outcomes may not necessarily be affected.
DOI	10.1177/0883073812465013
PMID	23143724