ホシノ ジユンイチ   Hoshino Jiyun'ichi
  星野 純一
   所属   医学部 医学科(東京女子医科大学病院)
   職種   教授・基幹分野長
論文種別 症例報告
言語種別 英語
査読の有無 査読あり
表題 Successful Discontinuation of Glucocorticoid Treatment after Administration of a Calcineurin Inhibitor for Nephrotic Syndrome in a Patient with Lupus Nephritis
掲載誌名 正式名:Internal medicine (Tokyo, Japan)
略  称:Intern Med
ISSNコード:13497235/09182918
掲載区分国外
巻・号・頁 62(7),pp.1037-1041
著者・共著者 Sawamura Masato, Sawa Naoki, Ikuma Daisuke, Oba Yuki, Yamanouchi Masayuki, Sekine Akinari, Mizuno Hiroki, Hasegawa Eiko, Suwabe Tatsuya, Hoshino Junichi, Kono Kei, Kinowaki Keiichi, Ohashi Kenichi, Ubara Yoshifumi
発行年月 2023/04/01
概要 Systemic lupus erythematosus was diagnosed in a patient at 43 years old. When proteinuria recurred at 57 years old, the first kidney biopsy was performed, and class IV-G (A) +V lupus nephritis was diagnosed. The prednisolone dose was increased to 40 mg/day, and cyclosporine A was introduced. After 1 year, proteinuria had decreased to 0.1 g/day. Prednisolone was discontinued three years later, and cyclosporine A was continued. Thereafter, proteinuria did not reoccur. At 67 years old, a second kidney biopsy showed complete remission of lupus nephritis. Cyclosporine A enabled permanent discontinuation of glucocorticoids in a patient with lupus nephritis.
DOI 10.2169/internalmedicine.0160-22
PMID 36070938