サイトウ　サトシ   Saitou Satoshi   斉藤　聡志    所属   医学部 医学科（東京女子医科大学病院）    職種   助教
論文種別	症例報告
言語種別	日本語
査読の有無	査読あり
表題	[Steroid pulse therapy was effective against anti-muscle-specific kinase antibody-positive myasthenia gravis crisis: a case report].
掲載誌名	正式名：Rinsho shinkeigaku = Clinical neurology 略　 称：Rinsho Shinkeigaku ISSNコード：18820654/0009918X
掲載区分	国内
巻・号・頁	63(6),379-381頁
著者・共著者	Saito Satoshi, Wako Syo, Kamada Ryusuke, Akiyama Shigeo, Hino Shuji
担当区分	筆頭著者,責任著者
発行年月	2023/06
概要	A 50-year-old woman experienced cardiopulmonary arrest. Although the arrest lasted for 4 min, she could not be withdrawn from the mechanical ventilator because of low tidal volume, despite being awake and alert after admission. The results of the anti-acetylcholine receptor antibody and repetitive nerve stimulation tests were negative, and the anti-muscle-specific kinase antibody levels revealed myasthenia gravis. We recommended therapeutic plasma exchange; however, the patient refused the treatment as she did not want to use blood products. Consequently, we initially attempted steroid pulse therapy, which enabled the patient to be withdrawn from the mechanical ventilator. Thus, steroid pulse therapy was beneficial for the crisis associated with the anti-muscle-specific kinase antibody in the absence of therapeutic plasma exchange.
DOI	10.5692/clinicalneurol.cn-001832
PMID	37197971