フナツ タカユキ   FUNATSU Takayuki
  船津 尭之
   所属   医学部 医学科(東京女子医科大学病院)
   職種   助教
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Comparison of practical methods in clinical sites for estimating cerebral blood flow during balloon test occlusion.
掲載誌名 正式名:Journal of neurosurgery
略  称:J Neurosurg
ISSNコード:19330693/00223085
掲載区分国外
巻・号・頁 pp.1-7
著者・共著者 Tani Shoichi, Imamura Hirotoshi, Asai Katsunori, Shimizu Kampei, Adachi Hidemitsu, Tokunaga So, Funatsu Takayuki, Suzuki Keita, Adachi Hiromasa, Kawabata Shuhei, Matsui Yuichi, Sasaki Natsuhi, Akiyama Ryo, Horiuchi Kazufumi, Sakai Chiaki, Sakai Nobuyuki
発行年月 2018/11
概要 OBJECTIVE:The authors sought to compare methods of measurement for venous phase delay (VPD) or mean stump pressure (MSTP) to rank their potential to predict ischemic tolerance during balloon test occlusion in the internal carotid artery, exploring a more correlative and convenient way to measure cerebral blood flow (CBF) that could be utilized even in the acute phase or in institutions not adequately equipped to measure CBF during the test.METHODS:X-ray angiography perfusion analysis using diagnostic digital subtraction angiography (DSA) equipment enables 1-step examination (without any room-to-room transfer of patients) to measure CBF, VPD, and MSTP completely simultaneously, which has not been accomplished by any previous perfusion studies.RESULTS:This analysis was applied to 17 patients and resulted in successful estimation of all 3 parameters in each case. The average VPD of several cortical veins had a strong correlation with relative CBF (rCBF) between bilateral hemispheres with a correlation coefficient of 0.89443, a correlation as strong as that (0.90357) of the "approximate VPD," which is interpreted based on the trend line of the scatterplot of the time to peak contrast opacification in cortical veins and their spatial positioning from the median sagittal plane. MSTP and classic visual determination of VPD have weaker correlation coefficients with rCBF (0.56119 and 0.70048, respectively). Overall, subjective visual determination in combination with the calculation of the trend line to estimate VPD provided a considerably strong correlation with rCBF (R = 0.86660) without any dedicated software or hardware.CONCLUSIONS:VPD has a stronger correlation with rCBF than MSTP. rCBF could be successfully predicted on common DSA equipment, even by visual determination without expensive software, if the trend line is adopted for processing to estimate VPD.
DOI 10.3171/2018.5.JNS18858
PMID 30497173