ツチヤ　ケン   Tsuchiya Ken   土谷　健    所属   医学部 医学科（東京女子医科大学病院）    職種   特任教授
論文種別	原著
言語種別	英語
査読の有無	査読なし
表題	Renal hyperparathyroidism.
掲載誌名	正式名：Vitamins and hormones 略　 称：Vitam Horm ISSNコード：00836729/00836729
巻・号・頁	120,pp.305-343
著者・共著者	Yajima Aiji, Tsuchiya Ken, Kuro-O Makoto, Urena Pablo, Tominaga Yoshihiro, Okada Manabu, Ichimori Toshihiro, Tomosugi Toshihide, Hiramitsu Takahisa, Murata Taro, Nakamura Masaki, Sasaki Masahiko, Ito Akemi, Nitta Kosaku
担当区分	2nd著者
発行年月	2022/07/22
概要	The number of the patients with chronic kidney disease is now increasing in the world. The pathophysiology of renal hyperparathyroidism is closely associated with Klotho-FGF-endocrine axes, which must be solved definitively as early as possible. It was revealed that the expression of fgf23 is activated by calciprotein particles, which induces vascular ossification. And it is well known that phosphorus overload directly increases parathyroid hormone and hyperparathyroid bone disease develops in those subjects. On the other hand, low turnover bone disease is often recently. Both the patients with chronic kidney disease suffering from hyperparathyroid bone disease or low turnover bone disease are associated with increased fracture risk. Micropetrosis may be one of the causes of increased fracture risk in the subjects with low turnover bone disease. In this chapter, we now describe the diagnosis, pathophysiology and treatments of renal hyperparathyroidism.
DOI	10.1016/bs.vh.2022.04.010
PMID	35953115