カクモト　アキナリ   KAKUMOTO Akinari
  覺本　晃成
   所属   医学部 医学科（附属足立医療センター）
   職種   助教
Article types Case report
Language English
Peer review Peer reviewed
Title Primary Hepatic Angioleiomyoma: A Case Report.
Journal Formal name：The American journal of case reports
Abbreviation：Am J Case Rep
ISSN code：19415923/19415923
Domestic / ForeginForegin
Volume, Issue, Page 24,pp.e938645
Author and coauthor Jamiyan Tsengelmaa†, Kuroda Hajime*, Luvsan Ganchudur, Munkhnyam Tserennadmid, Kakumoto Akinari, Enkhbat Bayarmaa
Publication date 2023/02
Summary BACKGROUND Primary hepatic angioleiomyoma is a rare mesenchymal tumor that is characterized by blood vessels and smooth muscle. Herein, we report an extremely rare case of primary hepatic angioleiomyoma and discuss the clinicopathological features. CASE REPORT A 60-year-old Mongolian man was diagnosed with a hepatic tumor in the second and third segments of screening in 2012. It had been under control by a physician for 10 years. The patient had discomfort and vague pain in the right side of the abdomen since April 2022. Hepatitis virus markers (hepatitis B and hepatitis C) were negative. Plain computed tomography revealed an 80-mm solitary liver lesion in the left lobe with well-defined margins and heterogeneous enhancement. A left hepatectomy was performed in May 2022. The cut surface of the tumor showed a grayish-white, elastic, hard mass with a diameter of 50×80 mm. Histological findings of the tumor revealed that it was clearly demarcated from the surrounding liver tissues with relatively clear boundaries showing thick, muscle-coated blood vessels with perivascular smooth muscle bundles. Immunohistochemical staining showed that the smooth muscle cells were strongly diffuse and positive for smooth muscle actin. CONCLUSIONS Clinically, primary hepatic angioleiomyoma should be distinguished from other types of liver tumors, especially liver cancer. In combination with our long-term observation and other case reports, we recommend general follow-up if the preoperative pathological diagnosis can be confirmed and the patient has no other symptoms.
DOI 10.12659/AJCR.938645
PMID 36805667