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タムラ マナブ
Tamura Manabu
田村 学 所属 研究施設 研究施設 職種 准教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Relationship between characteristics of glioma treatment and surgical site infections. |
| 掲載誌名 | 正式名：Acta neurochirurgica 略 称：Acta Neurochir (Wien) ISSNコード：09420940/00016268 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 165(3),pp.659-666 |
| 著者・共著者 | KUWANO Atsushi†, SAITO Taiichi, NITTA Masayuki, TSUZUKI Shunsuke, KORIYAMA Shunichi, TAMURA Manabu, IKUTA Soko, MASAMUNE Ken, MURAGAKI Yoshihiro, KAWAMATA Takakazu |
| 発行年月 | 2022/12/31 |
| 概要 | PURPOSE:Surgical site infections (SSIs) after neurosurgery are common in daily practice. Although numerous reports have described SSIs in neurosurgery, reports specific to gliomas are limited. This study aimed to investigate the relationship between SSIs and glioma treatment characteristics, such as reoperations, radiation therapy, and chemotherapy.METHODS:We examined 1012 consecutive patients who underwent craniotomy for glioma between November 2013 and March 2022. SSIs were defined as infections requiring reoperation during the observation period, regardless of their location. We retrospectively analyzed SSIs and patient factors.RESULTS:During the observation period, SSIs occurred in 3.1% (31/1012). In the univariate analysis, three or more surgeries (P = 0.007) and radiation therapy (P = 0.03) were associated with SSIs, whereas intraoperative magnetic resonance imaging (MRI) was not significantly associated (P = 0.35). Three or more surgeries and radiation therapy were significantly correlated with each other (P < .0001); therefore, they were analyzed separately in the multivariate analysis. Three or more surgeries were an independent factor triggering SSIs (P = 0.02); in contrast, radiation therapy was not an independent factor for SSIs (P = 0.07). Several SSIs localized in the skin occurred more than 1 year after surgery.CONCLUSIONS:Undergoing three or more surgeries for glioma is an independent risk factor for SSIs. Glioma SSIs can occur long after surgery. These results are considered characteristic of gliomas. We recommend careful long-term observation of patients at a high risk of SSIs. |
| DOI | 10.1007/s00701-022-05474-6 |
| PMID | 36585974 |