ホシノ　ジュンイチ   Hoshino Junichi   星野　純一    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Activity of daily life dependency predicts the risk of mortality in patients with COVID-19 undergoing hemodialysis: a retrospective analysis of a single center with nosocomial outbreak.
掲載誌名	正式名：Renal replacement therapy 略　 称：Ren Replace Ther ISSNコード：20591381/20591381
掲載区分	国外
巻・号・頁	8(1),pp.47
著者・共著者	Ino Jun, Iemura Fumika, Nakajima Chihiro, Kodama Mio, Kumon Saeko, Sato Keitaro, Eizumi Hitoshi, Hijikata Nobuhiro, Oshio Sadayuki, Tachibana Shingo, Nitta Kosaku, Hoshino Junichi
担当区分	最終著者
発行年月	2022/09
概要	BACKGROUND:We experienced a nosocomial outbreak of coronavirus disease 2019 (COVID-19) from November 2020 to February 2021, during the third wave of the pandemic in Japan.METHODS:We retrospectively assessed the characteristics and data of 20 inpatients undergoing hemodialysis who were hospitalized for treatment of diseases other than COVID-19 during the COVID-19 nosocomial outbreak ("inpatient," IP), and of 10 outpatients undergoing hemodialysis who were hospitalized for the care of COVID-19 under outpatient visits ("outpatient," OP).RESULTS:Eleven patients in the IP group (55%) and one in the OP group (10%) died. Kaplan-Meier analysis showed that the IP group died more rapidly than the OP group (p = 0.02). Multivariate analysis among all hemodialysis patients showed that the IP group was not at risk of mortality independently; however, the activity of daily life (ADL) dependency was found to be an independent factor in increasing the risk of mortality (hazard ratio: 7.618).CONCLUSION:Our findings show that the nosocomial infected group has a worse prognosis, although it is not an independent predictor for the risk of mortality. ADL dependency could predict the risk of mortality in all hemodialysis patients with COVID-19 during the third wave pandemic in Japan.
DOI	10.1186/s41100-022-00434-3
PMID	36101873