ワカバヤシ ヒデタカ   Wakabayashi Hidetaka
  若林 秀隆
   所属   医学部 医学科(東京女子医科大学病院)
   職種   教授・基幹分野長
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Association of Existence of Sarcopenia and Poor Recovery of Swallowing Function in Post-Stroke Patients with Severe Deglutition Disorder: A Multicenter Cohort Study.
掲載誌名 正式名:Nutrients
略  称:Nutrients
ISSNコード:20726643/20726643
掲載区分国外
巻・号・頁 14(19),pp.1
著者・共著者 Nishioka Shinta, Fujishima Ichiro, Kishima Masako, Ohno Tomohisa, Shimizu Akio, Shigematsu Takashi, Itoda Masataka, Wakabayashi Hidetaka, Kunieda Kenjiro, Oshima Fumiko, Ogawa Sumito, Fukuma Kazuki, Ogawa Nami, Kayashita Jun, Yamada Minoru, Mori Takashi, Onizuka Shinya
発行年月 2022/10
概要 BACKGROUND:The effect of sarcopenia on the recovery of swallowing function, and the interaction among sarcopenia, nutrition care, and rehabilitation therapy are inconclusive.METHODS:This multicenter cohort study was conducted between November 2018 and October 2020 in convalescent rehabilitation hospitals in Japan and included post-stroke patients aged ≥65 years with dysphagia. All participants were assigned to sarcopenia and non-sarcopenia groups. The primary outcome was the achievement of ≥2 Food Intake Level Scale [FILS] gain, and the secondary outcomes included Functional Independence Measure (FIM) gain and efficiency. Considering the effect modification of energy intake and rehabilitation duration, logistic regression analyses were performed.RESULTS:Overall, 153 participants with (median age, 82 years; 57.5% women) and 40 without (median age 75 years; 35.0% women) sarcopenia were included. The non-sarcopenia group had more patients who achieved an FILS gain of ≥2 (75.0%) than the sarcopenia group (51.0%). Sarcopenia was independently associated with a poor FILS gain (odds ratio:0.34, 95% confidence intervals: 0.13-0.86) but not associated with FIM gain or efficiency. This association was not affected by the rehabilitation duration or energy intake.CONCLUSIONS:In conclusion, sarcopenia was negatively associated with the recovery of swallowing function in stroke patients without interaction by energy intake and rehabilitation duration.
DOI 10.3390/nu14194115
PMID 36235767